BDBM50061975 CHEMBL3394229

SMILES Cc1cc2CC\C=C\Cc3c(O[C@H]4CC[C@H](N)CC4)cc(Cl)cc3C(=O)NCc2c(=O)[nH]1

InChI Key InChIKey=UGABIBYFHYMJLY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061975   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50061975(CHEMBL3394229)
Affinity DataIC50: 100nMAssay Description:Inhibition of methyltransferase activity of EZH2 within human PRC2 complex expressed in Sf9 cells assessed as transfer of tritiated methyl group from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50061975(CHEMBL3394229)
Affinity DataIC50: 32nMAssay Description:Inhibition of methyltransferase activity of EZH2 within human PRC2 complex expressed in Sf9 cells assessed as transfer of tritiated methyl group from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50061975(CHEMBL3394229)
Affinity DataIC50: 32nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed