BDBM50061880 1-(2-{3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicyclo[3.2.1]oct-8-yl}-ethyl)-1H-indole::CHEMBL3084928

SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccc(F)cc1)c1ccc(F)cc1)N2CCn1ccc2ccccc12

InChI Key InChIKey=LAWUACNPLAHCQV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061880   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061880(1-(2-{3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicy...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]WIN-35 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061880(1-(2-{3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicy...)
Affinity DataKi:  1.20E+3nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]DAU as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed