BDBM50061855 3-{3-[(5-Carbamimidoyl-benzofuran-2-carbonyl)-amino]-propionylamino}-3-(2,5-difluoro-phenyl)-propionic acid::CHEMBL137148

SMILES NC(=N)c1ccc2oc(cc2c1)C(=O)NCCC(=O)NC(CC(O)=O)c1cc(F)ccc1F

InChI Key InChIKey=AWHAGMFITVFACL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061855   

TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50061855(3-{3-[(5-Carbamimidoyl-benzofuran-2-carbonyl)-amin...)
Affinity DataIC50: 125nMAssay Description:Inhibitory activity of fibrinogen binding to purified immobilized glycoprotein (fibrinogen receptor).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50061855(3-{3-[(5-Carbamimidoyl-benzofuran-2-carbonyl)-amin...)
Affinity DataIC50: 300nMAssay Description:Inhibition of platelet aggregation induced by 20 uM adenosine 5'-diphosphate (ADP) in human platelet rich plasma (h-PRP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50061855(3-{3-[(5-Carbamimidoyl-benzofuran-2-carbonyl)-amin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of vitronectin binding to the purified immobilized vitronectin receptor (alpha v, beta 3).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed