BDBM50061823 1-[4-(8-Chloro-3-methyl-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-3-yl-ethanone::CHEMBL337193

SMILES [#6]-c1cnc2c(-[#6]-[#6]-c3cc(Cl)ccc3\[#6]-2=[#6]-2\[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#6]-c2cccnc2)c1

InChI Key InChIKey=KUNUOHGGLBDFJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061823   

LigandPNGBDBM50061823(1-[4-(8-Chloro-3-methyl-5,6-dihydro-benzo[5,6]cycl...)
Affinity DataIC50: 4.30E+4nMAssay Description:Compound was tested for the inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061823(1-[4-(8-Chloro-3-methyl-5,6-dihydro-benzo[5,6]cycl...)
Affinity DataIC50: 550nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed