BDBM50061811 1-[4-(8-Chloro-3-iodo-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-4-yl-ethanone::CHEMBL336219

SMILES Clc1ccc2c(-[#6]-[#6]-c3cc(I)cnc3\[#6]-2=[#6]-2/[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#6]-c2ccncc2)c1

InChI Key InChIKey=VGEQHXDORVLGLB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061811   

LigandPNGBDBM50061811(1-[4-(8-Chloro-3-iodo-5,6-dihydro-benzo[5,6]cycloh...)
Affinity DataIC50: 3.60E+4nMAssay Description:Compound was tested for the inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061811(1-[4-(8-Chloro-3-iodo-5,6-dihydro-benzo[5,6]cycloh...)
Affinity DataIC50: 68nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed