BDBM50061650 3-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-2,3-dihydro-benzo[1,4]dioxin-6-ol::CHEMBL135752

SMILES Nc1cccc(OCCCNCC2COc3ccc(O)cc3O2)c1

InChI Key InChIKey=XQRSLRUXPXVCRY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061650   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061650(3-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-2,3-d...)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061650(3-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-2,3-d...)
Affinity DataKi:  6.20nMAssay Description:In vitro binding affinity to rat hippocampal 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061650(3-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-2,3-d...)
Affinity DataKi:  24nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the antagonist [3H]spiperone + GTP to label the low affinity stat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed