BDBM50061640 (R)-2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; oxalic acid::CHEMBL135357

SMILES Oc1cc2O[C@@H](CNCc3ccccc3)CCc2cc1Cl

InChI Key InChIKey=BCTPODDQZONFKA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50061640   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061640((R)-2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; ...)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061640((R)-2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; ...)
Affinity DataKi:  2.20nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the antagonist [3H]spiperone + GTP to label the low affinity stat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061640((R)-2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; ...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity at human Dopamine receptor D3 (hD3) using [3H]spiperone radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061640((R)-2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; ...)
Affinity DataKi:  7nMAssay Description:Binding affinity at human Dopamine receptor D2 (hD2) using [3H]spiperone radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061640((R)-2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; ...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity at human Dopamine receptor D4 (hD4) using [3H]spiperone radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061640((R)-2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; ...)
Affinity DataKi:  214nMAssay Description:In vitro binding affinity to rat hippocampal 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed