BDBM50061639 2-{[(Thiophen-2-ylmethyl)-amino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL337724

SMILES Oc1ccc2CCC(CNCc3cccs3)Oc2c1

InChI Key InChIKey=KBNHFHXXRALJJY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061639   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061639(2-{[(Thiophen-2-ylmethyl)-amino]-methyl}-chroman-7...)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061639(2-{[(Thiophen-2-ylmethyl)-amino]-methyl}-chroman-7...)
Affinity DataKi:  2.80nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the antagonist [3H]spiperone + GTP to label the low affinity stat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061639(2-{[(Thiophen-2-ylmethyl)-amino]-methyl}-chroman-7...)
Affinity DataKi:  43nMAssay Description:In vitro binding affinity to rat hippocampal 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed