BDBM50061512 (S)-N*1*-(2-Benzooxazol-2-yl-1-methyl-2-oxo-ethyl)-2-[(S)-2-(3,3-dimethyl-butyrylamino)-3,3-dimethyl-butyrylamino]-N*4*,N*4*-dimethyl-succinamide::(S)-N1-(1-(benzo[d]oxazol-2-yl)-1-oxopropan-2-yl)-2-((S)-2-(3,3-dimethylbutanamido)-3,3-dimethylbutanamido)-N4,N4-dimethylsuccinamide::CHEMBL131909

SMILES CC(NC(=O)[C@H](CC(=O)N(C)C)NC(=O)[C@@H](NC(=O)CC(C)(C)C)C(C)(C)C)C(=O)c1nc2ccccc2o1

InChI Key InChIKey=UPZMULADGFTUKG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50061512   

TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061512((S)-N*1*-(2-Benzooxazol-2-yl-1-methyl-2-oxo-ethyl)...)
Affinity DataIC50: 600nMAssay Description:Micro molar potency to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061512((S)-N*1*-(2-Benzooxazol-2-yl-1-methyl-2-oxo-ethyl)...)
Affinity DataIC50: 3.00E+5nMAssay Description:Activity against serine protease human liver Cathepsin B (cat-B )More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061512((S)-N*1*-(2-Benzooxazol-2-yl-1-methyl-2-oxo-ethyl)...)
Affinity DataIC50: 3.00E+5nMAssay Description:Activity against serine protease bovine pancreatic Alpha-Chymotrypsinogen (BPC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-like elastase family member 2A(Pig)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061512((S)-N*1*-(2-Benzooxazol-2-yl-1-methyl-2-oxo-ethyl)...)
Affinity DataIC50: 80nMAssay Description:Activity against serine protease porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061512((S)-N*1*-(2-Benzooxazol-2-yl-1-methyl-2-oxo-ethyl)...)
Affinity DataIC50: 1.83E+5nMAssay Description:Binding affinity for human leukocyte elastase(HLE) serine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50061512((S)-N*1*-(2-Benzooxazol-2-yl-1-methyl-2-oxo-ethyl)...)
Affinity DataIC50: 80nMAssay Description:Inhibition of pig kidney PEPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed