BDBM50061252 1-Phenyl-2-(3-phenyl-8-aza-bicyclo[3.2.1]oct-8-yl)-ethanol::CHEMBL126742

SMILES OC(CN1C2CCC1CC(C2)c1ccccc1)c1ccccc1

InChI Key InChIKey=XTFPQFGGTSOHSO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061252   

TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061252(1-Phenyl-2-(3-phenyl-8-aza-bicyclo[3.2.1]oct-8-yl)...)
Affinity DataKi:  40.4nMAssay Description:Sigma-1 binding assay was done in guinea pig membranes by labeling the binding site with [3H](+)-pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061252(1-Phenyl-2-(3-phenyl-8-aza-bicyclo[3.2.1]oct-8-yl)...)
Affinity DataKi:  41.5nMAssay Description:Binding affinity for dopamine transporter was determined in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061252(1-Phenyl-2-(3-phenyl-8-aza-bicyclo[3.2.1]oct-8-yl)...)
Affinity DataKi:  474nMAssay Description:Binding to vesicular acetylcholine transporter of torpedo synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed