BDBM50061250 (3S,4S)-1-(3-Iodo-benzyl)-3-(3-phenyl-8-aza-bicyclo[3.2.1]oct-8-yl)-piperidin-4-ol::CHEMBL126762

SMILES O[C@H]1CCN(Cc2cccc(I)c2)C[C@@H]1N1C2CCC1CC(C2)c1ccccc1

InChI Key InChIKey=RZXQAOZBWNZIHX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50061250   

TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061250((3S,4S)-1-(3-Iodo-benzyl)-3-(3-phenyl-8-aza-bicycl...)
Affinity DataKi:  15nMAssay Description:Binding to vesicular acetylcholine transporter of torpedo synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061250((3S,4S)-1-(3-Iodo-benzyl)-3-(3-phenyl-8-aza-bicycl...)
Affinity DataKi:  195nMAssay Description:Sigma-1 binding assay was done in guinea pig membranes by labeling the binding site with [3H](+)-pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061250((3S,4S)-1-(3-Iodo-benzyl)-3-(3-phenyl-8-aza-bicycl...)
Affinity DataKi:  1.07E+3nMAssay Description:Binding affinity for dopamine transporter was determined in rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061250((3S,4S)-1-(3-Iodo-benzyl)-3-(3-phenyl-8-aza-bicycl...)
Affinity DataKi:  4.43E+3nMAssay Description:Binding affinity for serotonin transporter was determined in rat cortical membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed