BDBM50061112 9-Hydroxymethyl-6,6-dimethyl-3-pentyl-6H-benzo[c]chromen-1-ol::CHEMBL109972

SMILES CCCCCc1cc(O)c-2c(OC(C)(C)c3ccc(CO)cc-23)c1

InChI Key InChIKey=YDKZOUNVEIGJPO-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50061112   

TargetCannabinoid receptor 1(Rat)
Institute of Science

Curated by ChEMBL
LigandPNGBDBM50061112(9-Hydroxymethyl-6,6-dimethyl-3-pentyl-6H-benzo[c]c...)
Affinity DataEC50:  58nMAssay Description:Effective concentration for inhibition of Cannabinoid receptor 1-mediated adenylyl cyclase activity using African green monkey (COS-7) cells transfec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Institute of Science

Curated by ChEMBL
LigandPNGBDBM50061112(9-Hydroxymethyl-6,6-dimethyl-3-pentyl-6H-benzo[c]c...)
Affinity DataKi:  26.6nMAssay Description:Binding affinity to Cannabinoid receptor 2 using African green monkey (COS-7) cells Chinese hamster ovary(CHO) cells transfected with the cDNA of hum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Institute of Science

Curated by ChEMBL
LigandPNGBDBM50061112(9-Hydroxymethyl-6,6-dimethyl-3-pentyl-6H-benzo[c]c...)
Affinity DataKi:  38nMAssay Description:Binding to Cannabinoid receptor 1 using African green monkey (COS-7) cells transfected with the cDNA of rat CB1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Institute of Science

Curated by ChEMBL
LigandPNGBDBM50061112(9-Hydroxymethyl-6,6-dimethyl-3-pentyl-6H-benzo[c]c...)
Affinity DataKi:  189nMAssay Description:Binding affinity for Cannabinoid receptor 1 using African green monkey (COS-7) cells transfected with the cDNA of rat brain synaptosomal membrane pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed