BDBM50060966 4-Phenoxy-benzoic acid::CHEMBL107518::US10322118, Entry 11

SMILES c1ccc(cc1)Oc2ccc(cc2)C(=O)O

InChI Key InChIKey=RYAQFHLUEMJOMF-UHFFFAOYSA-N

Data  2 IC50  2 Kd

PDB links: 3 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060966   

TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060966(4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...)
Affinity DataKd:  9.10E+6nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50060966(4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...)
Affinity DataKd:  6.60E+5nMAssay Description:Binding affinity to native signal deficient and TEV cleavage site containing His-tagged Klebsiella pneumoniae OXA-48 expressed in Escherichia coli as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50060966(4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...)
Affinity DataIC50: 8.70E+5nMAssay Description:Inhibition of native signal containing Klebsiella pneumoniae OXA-48 using nitrocefin substrate pre-incubated for 5 mins before substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetPutative hydrolase(Pseudomonas aeruginosa (strain UCBPP-PA14))
Dartmouth College

US Patent
LigandPNGBDBM50060966(4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...)
Affinity DataIC50: 1.00E+5nMAssay Description:The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent