BDBM50060754 (S)-1-[(R)-3-(3,4-Dichloro-phenyl)-2-phenylmethanesulfonylamino-propionyl]-pyrrolidine-2-carboxylic acid benzylamide::CHEMBL123759

SMILES Clc1ccc(C[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N2CCC[C@H]2C(=O)NCc2ccccc2)cc1Cl

InChI Key InChIKey=DPAUUXUZXKZLOZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50060754   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060754((S)-1-[(R)-3-(3,4-Dichloro-phenyl)-2-phenylmethane...)
Affinity DataKi:  110nMAssay Description:In vitro inhibitory activity against human thrombin(IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060754((S)-1-[(R)-3-(3,4-Dichloro-phenyl)-2-phenylmethane...)
Affinity DataKi:  1.40E+4nMAssay Description:In vitro inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060754((S)-1-[(R)-3-(3,4-Dichloro-phenyl)-2-phenylmethane...)
Affinity DataKi:  3.84E+5nMAssay Description:In vitro inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed