BDBM50060725 2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxymethyl)-1-((S)-3-piperidin-3-yl-propyl)-1H-indol-3-yl]-ethanone::CHEMBL329536

SMILES Clc1ccc(OCc2c(C(=O)CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCC[C@@H]2CCCNC2)cc1

InChI Key InChIKey=XHHLNSWTGQCLAS-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50060725   

TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50060725(2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...)
Affinity DataKi:  0.75nMAssay Description:Binding affinity for Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50060725(2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...)
Affinity DataKi:  0.75nMAssay Description:In vitro binding affinity towards human neuropeptide Y receptor type 1, determined by measuring its ability to displace [125]peptide YYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50060725(2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...)
Affinity DataKi:  1.80nMAssay Description:Ability to reverse Neuropeptide Y receptor type 1-induced inhibition of forskolin-induced inhibition of forskolin-stimulated cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50060725(2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...)
Affinity DataKi: >1.00E+4nMAssay Description:Affinity for human Neuropeptide Y receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50060725(2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...)
Affinity DataKi: >1.00E+4nMAssay Description:Affinity for human Neuropeptide Y receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50060725(2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...)
Affinity DataKi: >1.00E+4nMAssay Description:Affinity for human Neuropeptide Y receptor type 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed