BDBM50060716 6-Bromo-5-[(2,5-dimethoxy-phenylamino)-methyl]-thieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL122259

SMILES COc1ccc(OC)c(NCc2c(Br)sc3nc(N)nc(N)c23)c1

InChI Key InChIKey=IUODCQSHQYCGJI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50060716   

TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060716(6-Bromo-5-[(2,5-dimethoxy-phenylamino)-methyl]-thi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060716(6-Bromo-5-[(2,5-dimethoxy-phenylamino)-methyl]-thi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060716(6-Bromo-5-[(2,5-dimethoxy-phenylamino)-methyl]-thi...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed