BDBM50060715 6-Bromo-5-[(3,5-dichloro-4-pyrrol-1-yl-phenylamino)-methyl]-thieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL331351

SMILES Nc1nc(N)c2c(CNc3cc(Cl)c(c(Cl)c3)-n3cccc3)c(Br)sc2n1

InChI Key InChIKey=BNDQSOWRPYRPJM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50060715   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060715(6-Bromo-5-[(3,5-dichloro-4-pyrrol-1-yl-phenylamino...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060715(6-Bromo-5-[(3,5-dichloro-4-pyrrol-1-yl-phenylamino...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060715(6-Bromo-5-[(3,5-dichloro-4-pyrrol-1-yl-phenylamino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed