BDBM50060481 5,6-Dihydro-benzo[c]acridin-7-ylamine::5,6-dihydrobenzo[c]acridin-7-amine::CHEMBL89012

SMILES Nc1c2CCc3ccccc3-c2nc2ccccc12

InChI Key InChIKey=FRXXZKCFLLWYIW-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50060481   

TargetSodium-dependent serotonin transporter(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060481(5,6-dihydrobenzo[c]acridin-7-amine | 5,6-Dihydro-b...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of neuronal uptake of 5 - Hydroxytryptamine in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060481(5,6-dihydrobenzo[c]acridin-7-amine | 5,6-Dihydro-b...)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of neuronal uptake of Noradrenaline in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060481(5,6-dihydrobenzo[c]acridin-7-amine | 5,6-Dihydro-b...)
Affinity DataIC50: 3.30E+3nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human plasma.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060481(5,6-dihydrobenzo[c]acridin-7-amine | 5,6-Dihydro-b...)
Affinity DataIC50: 3.74E+4nMAssay Description:In vitro inhibition of acetylcholinesterase, isolated from rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50060481(5,6-dihydrobenzo[c]acridin-7-amine | 5,6-Dihydro-b...)
Affinity DataIC50: 1.18E+3nMAssay Description:Compound was tested in vitro for inhibitory activity against ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetAcetylcholinesterase(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060481(5,6-dihydrobenzo[c]acridin-7-amine | 5,6-Dihydro-b...)
Affinity DataIC50: 4.00E+3nMAssay Description:Compound was tested in vitro for inhibitory activity against Acetylcholinesterase in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetAcetylcholinesterase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50060481(5,6-dihydrobenzo[c]acridin-7-amine | 5,6-Dihydro-b...)
Affinity DataIC50: 2.98E+3nMAssay Description:Compound was tested in vitro for inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetAcetylcholinesterase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50060481(5,6-dihydrobenzo[c]acridin-7-amine | 5,6-Dihydro-b...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed