BDBM50060457 (Z)-7-[(1S,2R,3R,4R)-3-(Naphthalene-2-sulfonylamino)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid::CHEMBL420507

SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=FIPYJDOEJWQULW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060457   

TargetProstaglandin D2 receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060457((Z)-7-[(1S,2R,3R,4R)-3-(Naphthalene-2-sulfonylamin...)
Affinity DataIC50: 420nMAssay Description:Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060457((Z)-7-[(1S,2R,3R,4R)-3-(Naphthalene-2-sulfonylamin...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of cAMP formation by carbacyclin in Prostaglandin I2 receptor (IP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060457((Z)-7-[(1S,2R,3R,4R)-3-(Naphthalene-2-sulfonylamin...)
Affinity DataIC50: 670nMAssay Description:Inhibition of [3H]- (+)-S-145 specific binding to human platelet membranes in TXA2 receptor (TP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060457((Z)-7-[(1S,2R,3R,4R)-3-(Naphthalene-2-sulfonylamin...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of [3H]PGD-2 specific binding to Prostaglandin D2 receptor from human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed