BDBM50060432 Benzyl-methyl-{(R)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-yl}-amine::CHEMBL324287

SMILES CN(Cc1ccccc1)[C@@H]1CCN(CCc2c[nH]c3ccc(cc23)-n2cnnc2)C1

InChI Key InChIKey=DGNFGNOCBIOZCU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060432   

Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060432(Benzyl-methyl-{(R)-1-[2-(5-[1,2,4]triazol-4-yl-1H-...)
Affinity DataIC50: 38nMAssay Description:Binding affinity by displacement to human cloned 5-hydroxytryptamine 1D receptor in CHO cells by [3H]5-HT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060432(Benzyl-methyl-{(R)-1-[2-(5-[1,2,4]triazol-4-yl-1H-...)
Affinity DataIC50: 210nMAssay Description:Binding affinity to human cloned 5-hydroxytryptamine 1B receptor in CHO cells by [3H]5-HT binding displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060432(Benzyl-methyl-{(R)-1-[2-(5-[1,2,4]triazol-4-yl-1H-...)
Affinity DataIC50: 209nMAssay Description:Displacement of [3H]5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060432(Benzyl-methyl-{(R)-1-[2-(5-[1,2,4]triazol-4-yl-1H-...)
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]5-HT binding from the cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed