BDBM50060043 3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-piperazin-1-yl-propyl]-benzamidine::CHEMBL319868

SMILES [H]/N=C(/c1cccc(c1)C[C@@H](C(=O)N2CCNCC2)NS(=O)(=O)c3ccc4ccccc4c3)N

InChI Key InChIKey=ZVDMTWWOKZXJOE-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50060043   

TargetSerine protease 1(Bovine)
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50060043(3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-piperaz...)
Affinity DataKi:  220nMAssay Description:Inhibitory activity against bovine trypsin expressed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50060043(3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-piperaz...)
Affinity DataKi:  220nMAssay Description:Tested for inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50060043(3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-piperaz...)
Affinity DataKi:  220nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50060043(3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-piperaz...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against bovine thrombin expressed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50060043(3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-piperaz...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50060043(3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-piperaz...)
Affinity DataKi:  1.02E+4nMAssay Description:Tested for inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50060043(3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-piperaz...)
Affinity DataKi:  1.02E+4nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50060043(3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-piperaz...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibitory activity against bovine coagulation factor X expressed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50060043(3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-piperaz...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50060043(3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-piperaz...)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibitory activity against human urokinase plasminogen activator expressed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50060043(3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-piperaz...)
Affinity DataKi:  4.80E+4nMAssay Description:Tested for inhibition of plasminogen activator urokinase (microPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed