BDBM50059977 6-Methyl-2-m-tolyl-1H-[1,8]naphthyridin-4-one::CHEMBL49016

SMILES Cc1cccc(c1)-c1cc(O)c2cc(C)cnc2n1

InChI Key InChIKey=KDLJOBRGZSEPQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059977   

TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059977(6-Methyl-2-m-tolyl-1H-[1,8]naphthyridin-4-one | CH...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50059977(6-Methyl-2-m-tolyl-1H-[1,8]naphthyridin-4-one | CH...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed