BDBM50059959 2-(3-Chloro-phenyl)-1H-[1,8]naphthyridin-4-one::CHEMBL45677

SMILES Oc1cc(nc2ncccc12)-c1cccc(Cl)c1

InChI Key InChIKey=HZSAAZXBYZMFJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059959   

TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059959(2-(3-Chloro-phenyl)-1H-[1,8]naphthyridin-4-one | C...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50059959(2-(3-Chloro-phenyl)-1H-[1,8]naphthyridin-4-one | C...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed