BDBM50059918 CHEMBL3394360

SMILES COCCc1ccc(cn1)-c1c(nc2c(nccn12)N1CCOCC1)C(F)(F)F

InChI Key InChIKey=VRNZUMSEKUGLPU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059918   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen Pharmaceutica

Curated by ChEMBL

LigandBDBM50059918(CHEMBL3394360)Copy SMILESCopy InChI

Affinity DataIC50: 282nMAssay Description:Inhibition of rat recombinant PDE10A expressed in Sf9 cells using [3H]cAMP substrate incubated for 60 mins by topcount scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/3/2016
Entry Details Article
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