BDBM50059890 2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b']difuran-4-yl)-ethylamine::CHEMBL316527

SMILES COc1c2OCCc2c(CCN)c2CCOc12

InChI Key InChIKey=NZPLNCQAEYLYII-UHFFFAOYSA-N

Data  6 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50059890   

Target5-hydroxytryptamine receptor 2C(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataKi:  62nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]DOI radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataKi:  205nMAssay Description:Antagonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]- rauwolscine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataKi:  302nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]5-HT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataKi:  335nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]DOI radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataKi:  654nMAssay Description:Antagonist activity at cloned human 5-hydroxytryptamine 2C receptor using [3H]mesulergine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataKi:  4.44E+3nMAssay Description:Antagonist activity at cloned human 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed