BDBM50059819 4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-dimethyl-benzamide::CHEMBL316845

SMILES COc1cccc(c1)[C@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccc(cc1)C(=O)N(C)C

InChI Key InChIKey=PVVQIDJUCGYOLM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059819   

TargetDelta-type opioid receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059819(4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataIC50: 18nMAssay Description:Binding affinity for Opioid receptor delta 1 by the inhibition of binding of [3H]-p-DPDPE human cloned receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059819(4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for Opioid receptor kappa 1 by the inhibition of binding of [3H]U-69593 in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059819(4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataIC50: 3.26E+3nMAssay Description:Binding affinity for Opioid receptor mu 1 by the inhibition of binding of [3H]DAMGO in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059819(4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataIC50: 4.80nMAssay Description:Binding affinity for Opioid receptor delta 1 by the inhibition of binding of [3H]DADAL in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059819(4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataIC50: 9.72E+3nMAssay Description:Binding affinity for micro receptors by the inhibition of binding of [3H]DAMGO to Opioid receptor mu 1 in human cloned receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed