BDBM50059790 CHEMBL3393803

SMILES FC(F)(F)c1cc(ccc1Cl)C(=O)Nc1ccc(Cl)c(c1)C(=O)Nc1ccc(nc1)-c1ncc[nH]1

InChI Key InChIKey=QEMXFLNJOAETGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059790   

TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50059790(CHEMBL3393803)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of human recombinant VEGFR2 incubated for 1 hr using [gamma-32P]ATP by top count assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50059790(CHEMBL3393803)
Affinity DataIC50: 650nMAssay Description:Inhibition of BRAF (unknown origin) incubated for 15 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed