BDBM50059721 4-Furan-3-yl-7-[2-(4-hydroxy-tetrahydro-pyran-4-yl)-pyridin-4-ylmethoxy]-naphthalene-2-carbonitrile::CHEMBL97923

SMILES OC1(CCOCC1)c1cc(COc2ccc3c(cc(cc3c2)C#N)-c2ccoc2)ccn1

InChI Key InChIKey=TZFLBFLRYWTQON-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059721   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50059721(4-Furan-3-yl-7-[2-(4-hydroxy-tetrahydro-pyran-4-yl...)
Affinity DataIC50: 350nMAssay Description:Compound was evaluated for the potency to inhibit oxidation of arachidonic acid by human recombinant 5-Lipoxygenase using a spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed