BDBM50059691 7-[(6-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-heptanoic acid::CHEMBL329571

SMILES NC(=N)c1ccc2cc([nH]c2c1)C(=O)NCCCCCCC(O)=O

InChI Key InChIKey=JGKQCWNXJDBDJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059691   

TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059691(7-[(6-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-h...)
Affinity DataIC50: 150nMAssay Description:Antagonism of fibrinogen binding to a purified human fibrinogen receptor preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059691(7-[(6-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-h...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of the platelet GPIIb-IIIa receptor measured as ability to attenuate ADP-induced (fibrinogen-mediated) platelet aggregation in human plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059691(7-[(6-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-h...)
Affinity DataIC50: 150nMAssay Description:Inhibition of platelet glycoprotein alpha IIb beta-3 integrin in ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article