BDBM50059689 (4-{[(5-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-methyl}-phenyl)-acetic acid::CHEMBL318903

SMILES NC(=N)c1ccc2[nH]c(cc2c1)C(=O)NCc1ccc(CC(O)=O)cc1

InChI Key InChIKey=VGBOGBRRHKVALF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059689   

TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059689((4-{[(5-Carbamimidoyl-1H-indole-2-carbonyl)-amino]...)
Affinity DataIC50: 1.40E+4nMAssay Description:Antagonism of fibrinogen binding to a purified human fibrinogen receptor preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059689((4-{[(5-Carbamimidoyl-1H-indole-2-carbonyl)-amino]...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of the platelet GPIIb-IIIa receptor measured as ability to attenuate ADP-induced (fibrinogen-mediated) platelet aggregation in human plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed