BDBM50059659 CHEMBL3393604

SMILES COc1ccc2OC(COc2c1)C(=O)NC(=O)N(CC(C)C)CC(=O)NCCCCCCNC(=O)c1ccc(cc1)-c1n[nH]c2ccccc12

InChI Key InChIKey=MBZXMVKLFZXZRB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059659   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50059659(CHEMBL3393604)
Affinity DataIC50: 99nMAssay Description:Inhibition of LRRK2 G2019S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Rat)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50059659(CHEMBL3393604)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of JNK3-mediated c-jun phosphorylation in rat INS1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50059659(CHEMBL3393604)
Affinity DataIC50: 12nMAssay Description:Inhibition of JNK3 (unknown origin) by JIP-FP displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50059659(CHEMBL3393604)
Affinity DataIC50: 109nMAssay Description:Inhibition of JNK1 (unknown origin) by JIP-FP displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50059659(CHEMBL3393604)
Affinity DataIC50: 336nMAssay Description:Inhibition of JNK2 (unknown origin) by JIP-FP displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed