BDBM50059498 3-(3,4-Dichloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL89913

SMILES COc1ccc2c3CCN(Cc4ccc(Cl)c(Cl)c4)Cc3c(=O)oc2c1

InChI Key InChIKey=CDPWDOLVSDDBEM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50059498   

TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059498(3-(3,4-Dichloro-benzyl)-8-methoxy-1,2,3,4-tetrahyd...)
Affinity DataKi:  61nMAssay Description:Ability to displace [3H]spiperone from cloned human Dopamine receptor D4 expressed in CHO K-1 cells in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059498(3-(3,4-Dichloro-benzyl)-8-methoxy-1,2,3,4-tetrahyd...)
Affinity DataKi:  61nMAssay Description:Binding affinity to human D4 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059498(3-(3,4-Dichloro-benzyl)-8-methoxy-1,2,3,4-tetrahyd...)
Affinity DataKi: >5.80E+3nMAssay Description:Ability to displace [3H]spiperone from human cloned Dopamine receptor D2 expressed in CHO K-1 cells in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059498(3-(3,4-Dichloro-benzyl)-8-methoxy-1,2,3,4-tetrahyd...)
Affinity DataKi: >5.80E+3nMAssay Description:Binding affinity to human D2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed