BDBM50059495 8-Methoxy-3-(4-nitro-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL88296

SMILES COc1ccc2c3CCN(Cc4ccc(cc4)[N+]([O-])=O)Cc3c(=O)oc2c1

InChI Key InChIKey=HHRUJJWXMZRWIG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059495   

TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059495(8-Methoxy-3-(4-nitro-benzyl)-1,2,3,4-tetrahydro-ch...)
Affinity DataKi:  7.5nMAssay Description:Ability to displace [3H]spiperone from cloned human Dopamine receptor D4 expressed in CHO K-1 cells in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059495(8-Methoxy-3-(4-nitro-benzyl)-1,2,3,4-tetrahydro-ch...)
Affinity DataKi: >3.00E+3nMAssay Description:Ability to displace [3H]spiperone from human cloned Dopamine receptor D3 expressed in CHO K-1 cells in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059495(8-Methoxy-3-(4-nitro-benzyl)-1,2,3,4-tetrahydro-ch...)
Affinity DataKi: >5.80E+3nMAssay Description:Ability to displace [3H]spiperone from human cloned Dopamine receptor D2 expressed in CHO K-1 cells in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed