BDBM50059494 3-(3-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one::CHEMBL90569

SMILES COc1ccc2c3CCN(Cc4cccc(Cl)c4)Cc3c(=O)oc2c1

InChI Key InChIKey=MMTKBQGOVDOJAE-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50059494   

TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059494(3-(3-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-c...)
Affinity DataKi:  17nMAssay Description:Ability to displace [3H]spiperone from cloned human Dopamine receptor D4 expressed in CHO K-1 cells in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059494(3-(3-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-c...)
Affinity DataKi:  17nMAssay Description:Binding affinity to human D4 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059494(3-(3-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-c...)
Affinity DataKi:  2.63E+3nMAssay Description:Ability to displace [3H]spiperone from human cloned Dopamine receptor D3 expressed in CHO K-1 cells in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50059494(3-(3-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-c...)
Affinity DataKi:  2.63E+3nMAssay Description:Binding affinity to human D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059494(3-(3-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-c...)
Affinity DataKi:  5.50E+3nMAssay Description:Ability to displace [3H]spiperone from human cloned Dopamine receptor D2 expressed in CHO K-1 cells in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059494(3-(3-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-c...)
Affinity DataKi:  5.50E+3nMAssay Description:Binding affinity to human D2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed