BDBM50059439 CHEMBL3393491

SMILES CCOC(=O)c1[nH]cc2C(c3ccc(Sc4nc5ccccc5[nH]4)o3)C3=C(CN(Cc4ccccc4)CC3=O)Nc12

InChI Key InChIKey=NYZJWCNLQGNIQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059439   

TargetAurora kinase A(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059439(CHEMBL3393491)
Affinity DataIC50: 11nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059439(CHEMBL3393491)
Affinity DataIC50: 8nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed