BDBM50059432 CHEMBL3393486

SMILES CCOC(=O)c1[nH]cc2[C@H](c3ccc(Sc4nc5c(F)cccc5[nH]4)o3)C3=C(CN(CC3=O)C(=O)CN)Nc12

InChI Key InChIKey=AHSNQEQSNWQRDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059432   

TargetAurora kinase A(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059432(CHEMBL3393486)
Affinity DataIC50: 15nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059432(CHEMBL3393486)
Affinity DataIC50: 2nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed