BDBM50059247 (7S,8S)-7,8-Dichloro-3-hydroxy-6,7,8,9-tetrahydro-1H-benzo[b]azepine-2,5-dione::CHEMBL82086

SMILES Oc1cc(=O)c2C[C@H](Cl)[C@@H](Cl)Cc2[nH]c1=O

InChI Key InChIKey=GCIQPALSSJZOGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059247   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50059247((7S,8S)-7,8-Dichloro-3-hydroxy-6,7,8,9-tetrahydro-...)
Affinity DataIC50: 130nMAssay Description:Antagonism of N-methyl-D-aspartate glutamate receptor 1 sites using [3H]DCKA as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50059247((7S,8S)-7,8-Dichloro-3-hydroxy-6,7,8,9-tetrahydro-...)
Affinity DataIC50: 131nMAssay Description:Tested for the inhibition of [3H]5,7-dichlorokynurenic acid (DCKA) binding to NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article