BDBM50059246 3-Hydroxy-7,8-dimethyl-6,7,8,9-tetrahydro-1H-benzo[b]azepine-2,5-dione::CHEMBL78784

SMILES CC1Cc2[nH]c(=O)c(O)cc(=O)c2CC1C

InChI Key InChIKey=FZAGXZARXIDXHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059246   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50059246(3-Hydroxy-7,8-dimethyl-6,7,8,9-tetrahydro-1H-benzo...)
Affinity DataIC50: 230nMAssay Description:Antagonism of N-methyl-D-aspartate glutamate receptor 1 glycine sites using [3H]DCKA as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50059246(3-Hydroxy-7,8-dimethyl-6,7,8,9-tetrahydro-1H-benzo...)
Affinity DataIC50: 228nMAssay Description:Tested for the inhibition of [3H]5,7-dichlorokynurenic acid (DCKA) binding to NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article