BDBM50059235 4-(5-Cyclohexyl-1H-pyrazol-3-yl)-1-phenethyl-piperidine::CHEMBL77744

SMILES C(Cc1ccccc1)N1CCC(CC1)c1cc(n[nH]1)C1CCCCC1

InChI Key InChIKey=XNFZPEDEZVYDIU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059235   

TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059235(4-(5-Cyclohexyl-1H-pyrazol-3-yl)-1-phenethyl-piper...)
Affinity DataKi:  10nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D4 (hD4) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059235(4-(5-Cyclohexyl-1H-pyrazol-3-yl)-1-phenethyl-piper...)
Affinity DataKi:  61nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059235(4-(5-Cyclohexyl-1H-pyrazol-3-yl)-1-phenethyl-piper...)
Affinity DataKi:  1.20E+3nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D3 (hD3) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed