BDBM50059219 4-(4-Methyl-5-phenyl-1H-pyrazol-3-yl)-1-phenethyl-1,2,3,6-tetrahydro-pyridine::CHEMBL80318

SMILES Cc1c(n[nH]c1C1=CCN(CCc2ccccc2)CC1)-c1ccccc1

InChI Key InChIKey=YYWRRBMZAGSBNZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059219   

TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059219(4-(4-Methyl-5-phenyl-1H-pyrazol-3-yl)-1-phenethyl-...)
Affinity DataKi:  3.10nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D4 (hD4) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059219(4-(4-Methyl-5-phenyl-1H-pyrazol-3-yl)-1-phenethyl-...)
Affinity DataKi:  90nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059219(4-(4-Methyl-5-phenyl-1H-pyrazol-3-yl)-1-phenethyl-...)
Affinity DataKi:  830nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D3 (hD3) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed