BDBM50059203 CHEMBL3393324

SMILES CC(=O)N1CCC(CC1)c1cc(Nc2cc(ccn2)C(F)(F)F)nc(n1)N1CCC(F)(F)C1

InChI Key InChIKey=JAXBPMVTQNGQOE-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059203   

LigandPNGBDBM50059203(CHEMBL3393324)
Affinity DataIC50: 300nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandPNGBDBM50059203(CHEMBL3393324)
Affinity DataKi:  33nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetProtein delta homolog 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50059203(CHEMBL3393324)
Affinity DataKi:  33nMAssay Description:Binding affinity to DLK (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed