BDBM50059054 5'-Methyl-2'-phenyl-3'-(phenylmethyl)spiro[cyclopentane-1,7'(8'H)-[3H]imidazo[2,1-b]purin]-4(5'H)-one::CHEMBL304161

SMILES CN1C2=NC3(CCCC3)CN2c2nc(-c3ccccc3)n(Cc3ccccc3)c2C1=O

InChI Key InChIKey=DHWNZBCSVBKPKZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50059054   

TargetPhosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059054(5'-Methyl-2'-phenyl-3'-(phenylmethyl)spiro[cyclope...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059054(5'-Methyl-2'-phenyl-3'-(phenylmethyl)spiro[cyclope...)
Affinity DataIC50: 11nMAssay Description:Evaluated for inhibitory activity against Phosphodiesterase 5 (PDE5) purified from bovine lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059054(5'-Methyl-2'-phenyl-3'-(phenylmethyl)spiro[cyclope...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Banasthali University

Curated by ChEMBL
LigandPNGBDBM50059054(5'-Methyl-2'-phenyl-3'-(phenylmethyl)spiro[cyclope...)
Affinity DataIC50: 11nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed