BDBM50058835 CHEMBL3325872

SMILES Cc1nn(c(N2CCOCC2)c1\C=N\Nc1nc2ccccc2nc1O)-c1ccccc1

InChI Key InChIKey=UCWKAKPLVUTIMU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50058835   

TargetProstaglandin G/H synthase 2(Sheep)
Dokki

Curated by ChEMBL
LigandPNGBDBM50058835(CHEMBL3325872)
Affinity DataIC50: 500nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production using arachidonic acid substrate by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Dokki

Curated by ChEMBL
LigandPNGBDBM50058835(CHEMBL3325872)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production using arachidonic acid substrate by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50058835(CHEMBL3325872)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50058835(CHEMBL3325872)
Affinity DataIC50: 500nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed