BDBM50058672 6-Methoxy-2,3,4,9-tetrahydro-beta-carbolin-1-one::6-methoxy-3,4-dihydro-2H-pyrido[3,4-b]indol-1(9H)-one::CHEMBL61505

SMILES COc1ccc2[nH]c3c(CCNC3=O)c2c1

InChI Key InChIKey=PWARHDUWOJUADN-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058672   

TargetMetabotropic glutamate receptor 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50058672(6-Methoxy-2,3,4,9-tetrahydro-beta-carbolin-1-one |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of intracellular calcium ion mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
University of Urbino

Curated by ChEMBL
LigandPNGBDBM50058672(6-Methoxy-2,3,4,9-tetrahydro-beta-carbolin-1-one |...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory activity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as radiolabeled ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
University of Urbino

Curated by ChEMBL
LigandPNGBDBM50058672(6-Methoxy-2,3,4,9-tetrahydro-beta-carbolin-1-one |...)
Affinity DataKi:  9.10E+3nMAssay Description:Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as labelled ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed