BDBM50058632 CHEMBL293141::N-[1-(2,2'-bithien-5-yl)ethyl]-N-hydroxyurea

SMILES CC(N(O)C(N)=O)c1ccc(s1)-c1cccs1

InChI Key InChIKey=LGHLTWATXWDXKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058632   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058632(N-[1-(2,2'-bithien-5-yl)ethyl]-N-hydroxyurea | CHE...)
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058632(N-[1-(2,2'-bithien-5-yl)ethyl]-N-hydroxyurea | CHE...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed