BDBM50058628 CHEMBL61974::N-hydroxy-N-[1-(3-phenoxyphenyl)ethyl]urea

SMILES CC(N(O)C(N)=O)c1cccc(Oc2ccccc2)c1

InChI Key InChIKey=KCVRPQFSQBKQLL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058628   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058628(N-hydroxy-N-[1-(3-phenoxyphenyl)ethyl]urea | CHEMB...)
Affinity DataIC50: 140nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed