BDBM50058622 CHEMBL61782::N-hydroxy-N-[1-(5-phenylthien-2-yl)ethyl]urea

SMILES CC(N(O)C(N)=O)c1ccc(s1)-c1ccccc1

InChI Key InChIKey=MDNYBMLOOGWOAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058622   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058622(N-hydroxy-N-[1-(5-phenylthien-2-yl)ethyl]urea | CH...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058622(N-hydroxy-N-[1-(5-phenylthien-2-yl)ethyl]urea | CH...)
Affinity DataIC50: 400nMAssay Description:Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed