BDBM50058600 CHEMBL292571::N-hydroxy-N-{1-[5-(phenylethynyl)-4,5-dihydrofuran-2-yl]ethyl}urea

SMILES CC(N(O)C(N)=O)c1ccc(\C=C\c2ccccc2)o1

InChI Key InChIKey=DETZRWQIKKMJDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058600   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058600(N-hydroxy-N-{1-[5-(phenylethynyl)-4,5-dihydrofuran...)
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed