BDBM50058521 2,4-Diamino-7-(2,6-dichloro-3,4,5-trimethoxy-phenyl)-7H-1,3,7,10-tetraaza-phenanthren-9-one::CHEMBL431740

SMILES COc1c(Cl)c(c(Cl)c(OC)c1OC)-n1ccc2c(c1)c(=O)nc1nc(N)nc(N)c21

InChI Key InChIKey=QGYFJGIUMVIQQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058521   

TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058521(2,4-Diamino-7-(2,6-dichloro-3,4,5-trimethoxy-pheny...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058521(2,4-Diamino-7-(2,6-dichloro-3,4,5-trimethoxy-pheny...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50058521(2,4-Diamino-7-(2,6-dichloro-3,4,5-trimethoxy-pheny...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed