BDBM50058481 (2R,3aR,7aR)-1-(2-{4-[(E)-3-(3,5-Di-tert-butyl-4-ethoxymethoxy-phenyl)-acryloylsulfamoyl]-benzoylamino}-3-methyl-butyryl)-octahydro-indole-2-carboxylic acid (3,3,3-trifluoro-1-isopropyl-2-oxo-propyl)-amide::CHEMBL292348

SMILES CCOCOc1c(cc(\C=C\C(=O)NS(=O)(=O)c2ccc(cc2)C(=O)NC(C(C)C)C(=O)N2[C@@H]3CCCC[C@@H]3C[C@@H]2C(=O)NC(C(C)C)C(=O)C(F)(F)F)cc1C(C)(C)C)C(C)(C)C

InChI Key InChIKey=BWFZIICRKOVHRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058481   

TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058481((2R,3aR,7aR)-1-(2-{4-[(E)-3-(3,5-Di-tert-butyl-4-e...)
Affinity DataIC50: 36nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed